HBV Special Interest Group 

The HBV Special Interest Group (SIG) is linked to the Viral CRN topic area. The SIG Lead is Dr Patrick Kennedy of the Royal London Hospital. The first meeting of the SIG was held in June 2018. If anyone wishes to join the group please contact the BASL secretariat on Samantha@basl.org.uk.

Aims

Define a strategic approach to recruit patients from centres across the UK encompassing the spectrum of HBV disease phases, to determine mechanisms underlying disease progression and treatment response, and to identify novel biomarkers in future hypothesis-driven research.

Document long-term clinical outcomes for the cohort, using both patient clinical records, and other linkable data sources, including routine laboratory surveillance, NHS Health and Social Care Information Centre datasets, and death and cancer registries. This would provide critical data on disease burden, natural history and use of NHS resources, and identify areas for intervention.

Involve patient and public representatives in a meaningful way to support investigators on study design, development and implementation, to ensure effective Patient-Public Involvement and Engagement.

 

 

 

Resources 

Annual reports

Annual report 2018-19 -  Download Annual report_2018-19_HBV SIG.pdf.

 

1st meeting - 28 June 2018

Presentation on HBV research in the UK, Will Irving, University of Nottingham - Download HBV Research UK.pdf.

Presentation on Hepatitis B priority areas, Sema Mandal and Samreen Ijaz, PHE - Download Hepatitis B priority areas.pdf.

Presentation on the HBV pipeline and what the SIG can offer, Geoff Dusheiko, Kings College Hospital - Download The HBV pipeline and what the SIG can offer.pdf.

Presentation on HBV immunological research, Salim Khakoo, University of Southampton -  Download HBV immunological research.pdf.

Presentation on HBV biomarkers, Ivana Carey, King’s College Hospital - Download HBV biomarkers.pdf.

 

2nd meeting - 31 January 2019

Meeting report -  Download The HBV SIG Jan 2019_Report.pdf.

 

3rd meeting - 11 July 2019

Presentation on attempts to secure funds for STORM HBV Consortium, John McLauchlan, Centre for Virus Research, Glasgow - Download Attempts to secure funds for STORM HBV Consortium.pdf.

Presentation on biomarkers of HBV transcriptional activity, Ivana Carey, Kings College Hospital, London - Download Biomarkers of HBV transcriptional activity.pdf.

Presentation on pitfalls of HBV DNA testing during NUC therapy, Anna Maria Geretti, University of Liverpool - Download Pitfalls of HBV DNA testing during NUC therapy.pdf.

Presentation on WHO hepatitis B elimination targets: How are we doing?, Ruth Simmons, PHE - Download WHO hepatitis B elimination targets _How are we doing.pdf

News

 Congratulations to Dr Patrick Kennedy who has been elected as Lead of the HBV SIG for the period July 2019 to July 2021.

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